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Ramachary D B

   Dr. D. B. Ramchary, Ph.D. ,
   Professor of Chemistry

   School of Chemistry
   University of Hyderabad
   Prof. C. R. Rao Road, Gachibowli
   Hyderabad, 500046, India
   Tel: 0091-40-23134816 
   Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it.


Ramachary obtained his Masters degree (General Chemistry) at the University of Hyderabad in 1996. There as part of curricula he studied and actively involved in the project, entitled Synthesis and Utilization of Aromatic Radical Anions for Reduction of Carbon Monoxide (with Prof. M. Periasamy).

Ramachary obtained his Doctoral degree (Organic Synthesis) at the Indian Institute of Science, Bangalore for his research work on Total Synthesis of Sesquiterpenes Containing Three Contiguous Quaternary Carbon Atoms (with Prof. A. Srikrishna).

In January 2002, he moved to Prof. Carlos F. Barabas III research group as Skaggs Post Doctoral fellow at The Scripps Research Institute, San Diego. After three year post doctoral studies at TSRI, he then joined as Faculty member in School of Chemistry, University of Hyderabad in Jan 2005, where at present he is a Reader.

Dr Ramachary has been awarded the INSA Medal for Young Scientists in Chemical Sciences for the year 2006 for his outstanding contributions to the emerging area of asymmetric organocatalysis.

The main focus of his research group is to engineer the novel and green asymmetric cascade and multi-component reactions (MCRs) to generate the biologically important molecules and natural products in a single step via emerging chiral amines or amino acid-catalysis.

His research group is actively engaged in the design and synthesis of novel enzyme mimetic small organic amines and amino acids to catalyze the fundamental organic reactions in enantioselective manner.

His interest about inquisitive questions like how small can be highly active and stereo-selective catalysts and what are the minimal functional and structural features required in a chiral catalyst had made him to venture in the most advanced versions of synthetic chemistry. 

For the more information about his research group please Click here for Home Page

Significant Publications:

D. B. Ramachary, M. Kishor and Y. Vijayendar Reddy, Development of Pharmaceutical Drugs, Drug Intermediates and Ingredients by Using Direct Organo-Click Reactions, Eur. J. Org. Chem., 2007, xxxx-xxxx (DOI: 10.1002/ejoc.200701014).

D. B. Ramachary, G. Babul Reddy and Rumpa Mondal, New Organocatalyst for Friedel-Crafts Alkylation of 2-Naphthols with Isatins: Application of an Organo-Click Strategy for the Cascade Synthesis of Highly Functionalized Molecules, Tetrahedron Lett., 2007, 48, 7618-7623.

D. B. Ramachary and M. Kishor, Organocatalytic Sequential One-Pot Double Cascade Asymmetric Synthesis of Wieland-Miescher Ketone Analogs from a Knoevenagel/Hydrogenation/Robinson Annulation Sequence: Scope and Applications of Organocatalytic Bio-Mimetic Reductions, J. Org. Chem., 2007, 72, 5056-5068.

D. B. Ramachary, K. Ramakumar and V. V. Narayana, Organocatalytic Cascade Reactions Based on Push-Pull Dienamine Platform: Synthesis of Highly Substituted Anilines, J. Org. Chem., 2007, 72, 1458-1463.

D. B. Ramachary and G. Babul Reddy, Towards Organo-Click Reactions: Development of Pharmaceutical Ingredients by Using Direct Organocatalytic Bio-Mimetic Reductions, Org. Biomol. Chem., 2006, 4, 4463-4468.

D. B. Ramachary and Rumpa Mondal, Direct Organocatalytic Hydroalkoxylation of a,b-Unsaturated Ketones, Tetrahedron Lett., 2006, 47, 7689-7693.

Jorly Joseph, D. B. Ramachary, Eluvathingal D. Jemmis, Electrostatic Repulsion as an additional Selectivity Factor in Asymmetric Proline Catalysis, Org. Biomol. Chem., 2006, 4, 2685-2689.

D. B. Ramachary, M. Kishor and G. Babul Reddy, Development of Drug Intermediates by Using Direct Organocatalytic Multi-Component Reactions, Org. Biomol. Chem., 2006, 4, 1641-1646.

D. B. Ramachary, M. Kishor and K. Ramakumar, A Novel and Green Protocol for Two-Carbon Homologation: A Direct Amino Acid/K2CO3-Catalyzed Four-Component Reaction of Aldehydes, Active Methylenes, Hantzsch Esters and Alkyl Halides, Tetrahedron Lett., 2006, 47, 651-656.

D. B. Ramachary, K. Ramakumar and M. Kishor, Direct Organocatalytic in situ Generation of Novel Push-Pull Dienamines: Application in Tandem Claisen-Schmidt/Iso-Aromatization Reactions, Tetrahedron Lett., 2005, 46, 7037-7042.

D. B. Ramachary and Carlos F. Barbas III, Direct Amino Acid-Catalyzed Asymmetric Desymmetrization of meso-Compounds: Tandem Aminoxylation/O-N Bond Heterolysis Reactions, Org. Lett., 2005, 7, 1577-1580.

D. B. Ramachary, Naidu S. Chowdari and Carlos F. Barbas III, Organocatalytic Asymmetric Domino Knoevenagel/Diels-Alder Reactions: A Bioorganic Approach to the Diastereospecific and Enantioselective Construction of Highly Substituted Spiro[5,5]undecane-1,5,9-triones, Angew. Chem. Int. Ed., 2003, 42, 4233-4237.