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Suresh Y

  Dr. Suresh Yenugu, Ph.D. (Osmania University, Hyderabad)
  Assistant Professor
  Department of Animal Sciences
  School of Life Sciences
  University of Hyderabad
  Prof. C.R.Rao Road, Gachibowli
  Hyderabad, 500046, India
  Tel: +91 40 23134579
  Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it. (or) This e-mail address is being protected from spambots. You need JavaScript enabled to view it.

Research Interests

My broad area of research is reproductive endocrinology, with specific emphasis on male reproductive tract immunology and contraception. The male reproductive tract is considered to be a vital organ system because of its indispensable functions. It plays a crucial role during development and fertility. In the recent years, attempts to understand male reproductive tract immunology has increased many fold due to the fact that identification of reproductive tract specific innate immune responses can help to combat sexually transmitted diseases, a serious problem on our country. When compared to other organ systems including the female reproductive tract, the male reproductive tract is known to express the highest number of defensins till date, suggesting the existence of sophisticated innate immune machinery. Defensins are a class of antimicrobial peptides that form the first line of defense. Besides the defensins, the male reproductive tract expresses a wide variety of proteins that conserve the characteristics of defensins, which have been shown to play a significant role in innate immunity besides their role in sperm maturation. Because of their dual role in immunity and sperm maturation, our goal is to identify the natural antimicrobial peptides of the male reproductive tract and exploit them to treat sexually transmitted diseases in place of conventional antibiotics, against which a variety of pathogens have developed resistance and also to use them as potential male contraceptives.

Awards/Achievements/Positions held

* DBT Postdoctoral fellow, Department of Biochemistry, Indian Institute of Science, Bangalore, Ocotober 1999 to May 2001.
* Fogarty International Trainee, Laboratories for Reproductive Biology, University of North Carolina, Chapel Hill, USA – June 2001 to May 2004.
* Research Associate, University of North Carolina, USA, June 2004 to Nov 2005.
* DST Young Scientist Award.
* DBT Overseas Associateship.
* ICMR-Tilak Venkobarao award.
* Academic Editor, PLoS ONE.

Recent Publications

  • Rajesh A, Yenugu S. Genomic organization, tissue distribution and functional characterization of the rat pate gene cluster. PLoS One. 2012; 7(3):e32633.
  • Madhubabu G, Yenugu S. Effect of continuous inhalation of allethrin-based mosquito coil smoke in the male reproductive tract of rats. Inhalation Toxicology. 2012; 24(3):143-52.
  • Narmadha G, Muneswararao K, Rajesh A, Yenugu S. Characterization of a novel lysozyme-like 4 gene in the rat. PLoS One. 2011; 6(11):627659.
  • Rajesh A, Madhubabu G, Yenugu S. Identification and characterization of Wfdc gene expression in the male reproductive tract of the rat. Mol Reprod Dev. 2011 Sep; 78(9):633-41.
  • Biswas B and Yenugu S. The Sperm Associated Antigen11 and defensin messenger RNA (mRNA) Expression In The Male Reproductive Tract Of Lipopolysaccharide Challenged Rats. Am J Reprod Immunol. 2011. 65(6): 557-68.