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Aparna Dutta Gupta

   Prof. Aparna Dutta Gupta, FNA, FASc, FNASc, FAAPS, Ph. D.
   (Banaras Hindu  University, Varanasi)

   Department of Animal Sciences
   School of Life Sciences
   University of Hyderabad
   Prof. C.R.Rao Road, Gachibowli,
   Hyderabad, 500046, India
   Tel: +91 40 23134560 /23010052 
   Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it. (or) This e-mail address is being protected from spambots. You need JavaScript enabled to view it.

Research Interests:

We carry out research in field of insect physiology, focusing pests, bearing a significant impact on their control. Our novel contribution includes that insect fat body expresses hexamerin genes and the expressed proteins are sequestered by various tissues including male accessory-glands and play role in reproduction. We have recently shown the presence of an aminopeptidase (Cry toxin receptor) in the visceral tissues like fat body, salivary gland and Malpighian tubules of lepidopteran larvae, which is a GPI-anchored protein. Hitherto, such receptors have only been reported from larval midgut, suggesting that the visceral organs could be exploited as alternate targets for Cry(Bt) toxin based insect pest management using a suitable delivery protocol. Significance of cocoon formation in lepidopteran pests is another aspect that could be used as an alternate strategy for pest control. Our recent work on silk genes, their hormonal regulation and identification of novel regulatory elements opens up a new avenue in this direction. We have identified several novel genes and their corresponding proteins, which could be exploited either for delivering or targeting molecules and/or growth regulators, which disrupt insect development, as the function of these genes/proteins is already validated, they could also be used to develop high throughput screening assays.

Awards/Achievements/Positions held

  • INSA-JSPS Bilateral Exchange Fellow, Miyazaki University, Japan (2012).
  • INSA-DFG International Exchange Fellow, Hamburg University, Germany (2008).
  • DST-DAAD Exchange Fellow, University of Wuerzberg, Germany (1999 – 2003).
  • INSA Exchange Fellowship, Czech Academy of Sciences, Czech Republic (2000).
  • Indo-German Exchange Programme Fellow, Univ. Tubingen, Germany (1991).
  • Fulbright Scholar & Visiting Scientist, Department of Biology, Marquette University, Milwaukee, USA (1984 – 1985).
  • Coordinator, Centre for Biotechnology (2003- 2006).
  • Served as Head, Department of Animal Sciences (2003-2007).

Recent Publications:

  • Chaitanya R.K., Sridevi P, Senthilkumaran B,  Dutta-Gupta, A. (2012)  Effect of juvenile hormone analog, methoprene on H-fibroin regulation during the last instar larval development of Corcyra cephalonica. Gen. Comp. Endocrinol., doi10.106/j.ygcem.2012.08.014.
  • Parikipandla Sridevi, R. K. Chaitanya, Aparna Dutta-Gupta, Balasubramanian Senthilkumaran (2012) FTZ-F1 and FOXL2 up-regulate catfish brain aromatase gene transcription by specific binding to the promoter motifs. Biochim. Biophys. Acta, 1819, 57-66.
  • Parikipandla Sridevi, Aparna Dutta-Gupta, Balasubramanian Senthilkumaran (2011) Molecular cloning and expression analysis of fushi tarazu factor 1 in brain of airbreathing catfish, Clarias gariepinus. PLoS One 6(12):e28867.
  • Madhusudhan Budatha, Thuirei Jacob Ningshen and Aparna Dutta-Gupta (2011) Is hexamerin receptor a GPI anchored protein in Achaea janata (Lepidoptera: Noctuidae)? J. Biosciences, 36, 545-553.
  • Chaitanya RK, Sridevi P, Senthilkumaran B, Dutta-Gupta A. (2011) 20-Hydroxyecdysone regulation of H-fibroin gene in the stored grain pest, Corcyra cephalonica, during the last instar larval development. Steroids, 76, 125-134.